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These indications have been recognized as an effective treatment by the Undersea and Hyperbaric Medical Society:

• embolisms (air or gas bubbles in the bloodstream, which may travel to the brain or lungs);
• carbon monoxide poisoning (from inhaling smoke or car exhaust);
• gas gangrene;
• crush injury, Compartment Syndrome and other acute traumatic problems where blood flow is reduced or cut off (e.g., frostbite);
• decompression sickness (the bends);
• enhancement of healing for wounds such as diabetic foot ulcers;
• exceptional blood loss (anemia);
• intracranial abscess (an accumulation of pus in the brain);
• necrotizing soft tissue infections (flesh-eating disease);
• osteomyelitis (bone infection);
• delayed radiation injury (e.g., radiation burns that develop after cancer therapy);
• skin grafts and flaps that are not healing well; and
• thermal burns (e.g., from fire or electrical sources).